Application of glucocorticoids in treatment of COVID-19.

The infection of 2019-nCoV can lead to overexpression of inflammatory factors, triggering cytokine storm and causing serious damage to the body. Glucocorticoids have anti-inflammatory properties and may be an effective treatment option. The use and dosage of glucocorticoids in coronavirus disease 2019 (COVID-19) remains controversial. This article reviews the theoretical basis, clinical evidence, debates and specific measures of glucocorticoids in the treatment of COVID-19, to provide reference for rational application of glucocorticoids in the future.Copyright © 2021 Chinese Medical Association

Will COVID-19 be the trigger point for developing visitor attraction revenue management?

Purpose The purpose of the paper is to explore how the effects of the COVID-19 pandemic will influence the development of revenue management practice in the visitor attractions sector. Design/methodology/approach This viewpoint paper builds on the argument that tracking previous patterns of behaviour and trends can be used to predict future actions and developments. Findings The paper identifies how historically the development of revenue management practice has been driven by major external trigger points often linked to sudden increases in competitive pressures, such as the deregulation of the airline industry, and expands on this to argue that the pandemic is one such trigger point that has fundamentally changed the approach to revenue management through a refocusing on key principles to manage demand and that this could potentially accelerate its development within the visitor attraction sector. Originality/value Pre-COVID, the practice of revenue management in the visitor attraction sector was underdeveloped, and the opportunities to develop revenue management had not been discussed in the academic literature. This paper suggests that the challenges of the pandemic that forced visitor attractions to focus on visitor demand management can now begin to be extended to incorporate the management of revenue and will consequently be of value for academics and practitioners.

Futurology and monitoring in the field of virology to deal with emerging diseases

Every year we see many changes in the world around us. One of these changes is the climate and weather, and it could be one of the reasons for changing behaviors between humans and animals, which could cause zoonotic diseases. We usually face new diseases that infect a growing population leading to a pandemic. Different reasons are leading to an increase in the emergence of new infections. Some of these diseases can be associated with zoonotic diseases and the diverse world of viral genetics and its failures. Furthermore, properties like mutations and also unknown effects of these mutations on the virulence of the agents make it challenging to trace new diseases. As we know, preventing emerging diseases is inevitable and viral diseases are dangerous, and some viruses can spread quickly and cause an endemic or pandemic. As was noticed during the recent pandemic, the need to study emerging diseases in the field of virology has become more and more apparent to us. In this review, we want to look at how we could monitor and control these diseases with new approaches and what should be done when a disease emerges. Moreover, we will investigate risk factors, ways to deal with emerging viral infections, new treatments that make the condition better when a person gets infected, and the future of these diseases. We will also study the ways to deal with pandemics with the new generations of vaccines.